Though not a samurai, he appears to maintain a certain degree of bushido, and is frequently mistaken for one. Unlike Luffy and most of the other Straw Hat pirates, Zoro has been known to kill his opponents if he has to, though never in cold blood. Zoro has a stern, serious and distanced personality, but, unlike Robin, he often reacts in a goofy and exaggerated comic style due to his gruff, impatient attitude. On the ship, he normally either trains with weights or sleeps. The only work he is seen doing regularly is hoisting the anchor using his great strength. He also likes sake, almost to the degree that Luffy likes meat, but like Nami, he never gets drunk due to his inhumanly-high endurance and tolerance for alcohol. Another notable trait is his lack of orientation, as Zoro often gets lost, even in small, familiar spaces or when being led by someone. Despite this, he is often the first to sense an enemy or danger, and the first to react. He is often displayed being well aware of dangerous situations and people around him. Zoro often also reminds others of the harsh facts, which often shocks some of the other crew members, although they usually decide he is right. Zoro has also stated that he is an atheist, and has never believed in anything except himself. He often comes across as arrogant and overconfident, but only because he knows he's a strong man with great fighting ability. Even so, Zoro knows that he still has a lot of untapped potential, and is constantly seen training and trying to improve his fighting skills. He also adheres to a strict sword master's code of honor, and never falsely brags or lies about his abilities, sometimes outright admitting a weakness, even to an enemy. He also never tries to escape from a fight or use trickery to win, believing that doing so is cowardly and scorning anyone who uses such tactics. Zoro is very vigorous, strong-willed, and determined.

Edward "Fullmetal Alchemist" Elric is a young alchemical prodigy. He is the youngest State Alchemist ever to be recognized by the Amestris State Military, having received the title at the age of 12. Ed's primary motivation throughout the series is to return his younger brother, Alphonse, to his original body, which was lost in a failed human transmutation. Edward, despite his occasional bouts of immaturity, is a selfless boy who gains a reputation as a "hero of the people" throughout his youth. Notably, he doesn't seem concerned about returning his own arm and leg, instead focusing entirely on Al's suffering. Edward is small for his age, standing at only 149 cm (4'11"), however, his body is that of an experienced martial artist, with noticeable muscles and a wealth of agility. Although he lacks both his right arm and left leg, Ed's ability to fight is not impaired and is in fact improved, as he will often use alchemy to cause his metal arm to partly transform into a blade or shield. His heavy automail limbs are considered by him to be the very best in Amestris. They were made by his childhood friend, Winry Rockbell, and she is constantly working on them. He is able to think quickly, even in desperate situations, though can still be frightened into paralysis. These qualities, combined with his alchemical powers and physical strength, make him a formidable fighter. Born to Trisha Elric and Van Hohenheim of Resembool in the winter of 1899, Edward's first few years were relatively happy; but after the sudden departure of his father during the lad's formative years, Ed was left with his mother and younger brother Alphonse as his only family. The three Elrics lived in peace in the rural village and the boys began displaying a remarkable talent for alchemy at a young age, much to the joyful astonishment of his mother. However, early in the year 1904, Trisha contracted an illness that had been spreading in the area and died, leaving her two sons orphaned. Even while mourning, mired in grief, Edward vowed to his brother that the two of them would find a way to bring their dead mother back to life with the power of alchemy. Edward and Alphonse spent the next few years living on their own in the Elric family home, supported by their close childhood friend Winry Rockbell and her grandmother Pinako, and pursuing the alchemical knowledge necessary for their planned resurrection. Although they had gained a great deal of information and comprehension regarding the extended basics of the craft, before long it became apparent to the young prodigies that there was only so far they could go while being self-taught. In a stroke of good fortune, Resembool was visited by an exceptionally skilled alchemist named Izumi Curtis who, after some persuasion, agreed to take the Elric brothers on as her apprentices provided they pass a preliminary test. After they do, the Elric brothers were subjected to Izumi's intensive alchemy and martial arts training, growing significantly in both mind and body and gaining a great deal of alchemical knowledge before returning to Resembool. Though instructed specifically by Izumi to understand that death is an irreversible part of the flow of the world and that acceptance of such is important to the "One is All, All is One" concept, the boys dove headlong into their plan to resurrect their mother upon their homecoming, having advanced their knowledge while abroad and discovered the basics of a forbidden practice called Human Transmutation. Devising a Human Transmutation Circle, amassing the elemental ingredients for an adult human body and offering their own blood as soul and biological data, the boys secretly initiated the Human Transmutation in their home. Unfortunately, the Human Transmutation resulted in a Rebound. Alphonse and Edward were pulled into The Gate. Encountering the mysterious being called Truth, Edward was stripped of his left leg in exchange for crossing into God's domain and peeking at the Gate's vast wealth of alchemical knowledge. Maimed and bleeding, Edward was returned to the human dimension to find that Alphonse had not yet returned from his disappearance into the Gate, that the mother they had attempted to revive was a grotesque mass of organs only capable of sustaining life for a few moments and that his own sojourn into the Gate had granted him the curious ability to perform transmutations merely by clapping his hands together, without the aid of a Transmutation Circle - in the same style used by Izumi. Desperate to at least have his brother by his side, Edward willfully performed another Human Transmutation to call him back, this time sacrificing his right arm in exchange for Al's soul, which he bound alchemically to an antique suit of armor with a Blood Rune before passing out from severe blood loss. Alphonse carried Ed to the Rockbell house, where a shocked Pinako and Winry performed emergency surgery to save the young boy's life. On the night of the failed transmutation. Lt. Colonel Flame Alchemist Roy Mustang came to the Rockbell's in response to a letter that Edward and Alphonse had sent him in the mail asking about their Father. He was shocked at the fact that the two boys had tried human alchemy and survived, and informed them that they could become state alchemist and maybe one day find a way to return their bodies to the way they were. Desperate to get His younger brother's body back, Edward asked the Rockbells to give him prosthetic limbs called automail. Though they warned him the surgery would be painful, he said the pain was nothing compared to what his brother had given up. He only took a year to adapt to the automail at age 11 when it took most adults three years.