Hitagi, a main female character of Bakemonogatari, is a weak-looking girl with an "incurable disease." She is in the same class as Koyomi, but he has almost never heard her speak. When she was in the first year of high school, she encountered a mysterious crab, after which she became nearly weightless. Ever since then, she has avoided contact with everyone else, threatening everyone who discovers her secret. She jokingly labels herself as a tsundere and speaks with a sharp tongue.
Tsukuyo is a blonde-haired woman with a scar over her forehead and left cheek. One of the better known Hundred Blooms of Yoshiwara, a law enforcement squad of Yoshiwara that consists of all females, deployed by the Night King Hosen. Despite appearing to be a heartless person when approached by Odd Jobs when he arrives to Yoshiwara, throwing a fake kunai to their foreheads, she later becomes friends with them. She has a difficult past being orphaned as a child, only to be picked up and raised by a ruthless and deadly assassin, Jiraia. While the original motive for Jiraia was to instill every bit of despair and tragedy of his own life into Tsukuyo, of who he refers to as his art or perfect creation, Tsukuyo ended up growing attached to what he did not manage to do. That is "Friends, A Home, and Precious Things To Protect" as told by Jiraia. Her loyalty and home lies with Hinowa in the underground city of Yoshiwara. She has ties with Hinowa, who also helped raise her like an older sister/mother through her childhood. (Source: Wikipedia)