Clare is the series' protagonist. In the beginning of the series she is number 47 of the organization's 78th generation, making her the lowest ranked claymore. She also holds the distinction of becoming the first individual to willingly become a claymore. She saves Raki from a youma and takes him under her care because he reminds her of herself when she was younger.

Jonathan Joestar is the protagonist of Part 1: Phantom Blood, and the first JoJo of the JoJo's Bizarre Adventure series. The son of George Joestar I, Jonathan is an honest, kind, and positive man whose life is fraught with tragedy after meeting his adopted older brother, Dio Brando. As a gentleman, Jonathan is kind and cheerful. Jonathan has a mindset where he tries to imagine the consequences his actions would have on other people, even if they appear to be enemies. He is gentle and sympathetic, feeling pain even as he defeats a zombified copper. Despite his skill in fighting, he will never seriously harm a person without a valid reason. Yet Jonathan can feel righteous fury at the evilness of his foes and will conduct justice by defeating them. Furthermore, he does not pity truly despicable individuals he is not familiar with, such as Doobie. With his courage and spirit, Jonathan sets a legacy as the first JoJo of the series. Legacy (future parts): (Source: JoJo's Bizarre Wiki Adventure, edited)