Kamina is a young man from Jiiha village who dreams of leaving the village and go to the surface, which he saw as a kid. He's very passionate about his goals, expressing his wishes through energetic speeches, which seems to affect all those who hear him. He convinces Simon to help him with his plan to drill through the roof of the village and get to the world above, but the plan failed and he was put in prison. He left the village shortly thereafter with the help of Simon and a young girl named Yoko, as a result of fighting a Gunmen, who broke into the village from the surface. After he, Simon, and Yoko break through, they meet many enemies and friends as they go, to the point of building up a resistance force, the Gurren Brigade to fight in their war against the Beastmen Empire who hunt on human beings who live on surface, and becoming their leader. (Source: Wikipedia)

A calligrapher who disgraced himself by punching a director of an art gallery who criticized his calligraphy style heavily as "boring," "rigid," "academic," and "bland." He then leaves for the Goto Islands in Nagasaki at the suggestion of his famous calligrapher father to focus more on his calligraphy as he waits out his "exile." Along the way, he finds value in interactions with other people, in particular a tomboyish little girl named Naru, and finds his inspiration and own personal style. At first, Naru calls him "Junon Boy," referring to a particular magazine that features street pictures of male idols, suggesting (incorrectly) that he's a city-dwelling pretty boy of the kind that don't really exist in real life. Later on, she calls him, "Sensei." Sei Handa appears again in another manga titled Handa-kun, a prequel of sorts featuring Handa during his high school years. In the prequel, he is a well-regarded school idol and prodigy calligrapher who holds the hilariously mistaken belief that no one likes him and that the distantly worshipful actions of his peers is in fact bullying. This is apparently the fault of his best friend of both series, Kawafuji, who told him a lie that he was "hated" as a joke, which Handa mistook for the truth, and his friend never actually tried to correct because he found it funny and amusing.